Abstract:acetone catalyzed chloride uye inogadzirwa ne solvent crystallization pa1,1,3-trichloroacetone ine hutsanana hwepamusoro husingasviki 99.0%,negoho re45%o Mazwi akakosha:1,1,3-trichloroacetone;synthesis;kuchena kwakanyanya

———-. Nhanganyaya

1,1,3■trichloroacetone inokosha yepakati mukugadzirwa kwefolic acid.Parizvino,1,1,3.acetone trihloropacetone,kurebesa kwekugadzirwa kwemaawa(48 maawa),kusaita zvakanaka,goho rakaderera,1,1,3- trichlorropacetone content inongosvika 17%,mushure mekudzurwa kwemvura,zvirimo ingori 51.9%.Uye mutengo wekugadzira wakakwira,chigadzirwa chekugadzirisa chakaderera.Izvi zvese zvinotungamira kumitengo yepamusoro yekugadzira folic acid yemumba,yakaoma kuvandudza zvirimo nezvimwe. matambudziko.Munyori akaverenga nhamba huru yemagwaro epamba neekunze. Mushure mekuedza kwakawanda uye zvidzidzo, takawedzera catalyst uye kudzora fou chlorine kumhanya, kuderedza nguva yekuita kusvika 1,1,3-3 trichlorropacetone mumaawa makumi maviri nemana, uye 1,1,3-3 trichlorropacetone crystallization nekuchena kukuru kupfuura 99% uye goho rinodarika 45%.

II. Chikamu chekuedza

1. reaction

0 0 0

1. II.

　　CHACCHa+Cl:—ClCH.₂CCH.₃+Cl.₂CHCCH.₃+C1CH.₂CCH.₂C1+

1. Kuedza matanho

Mubhodhoro remitsipa mina rine 500ml spherical condenser, imwe acetone uye catalyst yakamutswa uye yakadyiswa ku chlorine painodziya tembiricha ye10 ~ 30 W. Tanga nguva, rega kupfuura neklorine maawa akawanda mushure mekuita, uye enderera mberi. kubvongodza kweawa 1. Mushonga unokosha wakaita sechinhu wakawedzerwa kumusanganiswa unoguma, wakasvetwa kweawa imwe uchitonhorera kusvika ku10 ° C crystallization, uchibvisa 1,1,3-trichloroacetone.

1. 1,1,3.Kusarudza kusarudza kwe trichloroacetone kuchena

Varin 3700 gasi chromatograph, QF ・ 1 mbiru yekuzadza uye FID detector yakashandiswa kusarudza kuchena purofiti yechigadzirwa uye chloride mhinduro.

1. Migumisiro yehurukuro
2. Pesvedzero yecatalyst pane chloride selectivity yakaratidza kusarudzwa kweacetone chlorination

Kupesvedzera kukuru, Tafura 1 inoronga seti yezviyedzo zvabuda.Kubva paTafura 1, kushomeka kwekusarudza kwe1,1,3-trichloroacetone inowedzerwa zvakanyanya (inenge 19.1%) pasina catalyst, uye

　　compound amine catalyst ndiyo yakanakisisa, inosvika 57.5% o.Test conditions: Innl acetone, 3nr) l chlorine, catalyst 0.6g, tembiricha 1030°C,

nguva maawa 18.Mukati maawa gumi nemaviri va:3.9 Cao h;2

〜7 maawa,vq:27 Cao h;7〜18 maawa,VQ:3.9 kusvika h.Tafura 1.Migumisiro yecatalyst pakusarudza chigadzirwa

1. Mhedzisiro ye-ku-chlorine velocity pane maitiro

Chiyedzo chakawana kuti yunifomu yeklorini yakanga isina kusarudzika kwechigadzirwa, ichivandudza zvakanyanya kusarudzwa kwechigadzirwa uye goho.

Tafura 2 inoronga seti yedata rekuyedza.

Tafura 2 Migumisiro yepass-chlorine velocity pakusarudza chigadzirwa

Muedzo^mamiriro:]Petri dish 1 acetone,catalyst:composite class 0.6go

Chiyedzo chakawana kuti fluchlorine yakakurumidza (maawa gumi nemaviri) uye gare gare (8 24 h), chlorine yakawanda inopukunyuka kuti mhinduro yainonoka uye yepakati (28 h) yaikurumidza. Kana gasi rechlorine ramiswa, kusarudzwa kwechigadzirwa uye goho. zvakaderedzwa zvakanyanya.Zvigumisiro zvakaratidza kuti 1,1,3 yakabudisa zvishoma kudarika

1,1-dichloroacetone.Panguva yekupindura ne

chloride, chloride, acetone, 1,1,4003000,

CICH2CCH3

o.

ndizvo_II.chlorination pane submethyl boka yaive yakawanda

nekukurumidza kupfuura pane methyl group. Naizvozvo, the

munyori anotenda kuti acetone chloride generation process reaction process ndeye:

Kuita kunoitwa neV1 1 2-5 senzira huru.

Zvinoenderana neiyo Tafura 2 data, iyo reaction velocity kurongeka kwenhanho imwe neimwe ndeye

　　V2^”3^1 2 5>V4

Zvichienderana nekumhanya kwekuita kwedanho rega rega,

Zvinogona kuonekwa kubva kudata reTafura 3 kuti,nekuda kwekamusiyano kadiki kekubikira pakati pe1,1,3.trichloroacetone ne-by-products,zvinowanzonetsa kuparadzanisa kubviswa kwemvura uye kupatsanura inzira iri nyore.Kunyange zvazvo vazhinji I zvigadzirwa zvinogona kubviswa, kuchena kwakaoma

isu tinodzora kupfuura chlorine kumhanya padanho rega rega,

kuzadzisa chinangwa chekudzikisa kupfuudza kweklorini nguva uye kurambidza kusarudzwa kwekuwedzera yechipiri yekupindura kumhanya ne1,1,3 trichloroacetone.

1. Hydrated crystal kucheneswa Zvinoenderana nezvinyorwa, kazhinji iyo

acetone chloride liquid inobviswa kana kunatswa nemvura kuti iwedzere zviri mukati me1,1,3-trichloroacetone, uye munyori akashandisa 1,1,3-trichloroacetone ku crystallization kubva kune zvimwe zvigadzirwa.

Tafura 3 inonyora kuchena kwechigadzirwa kunowanikwa nenzira dzakasiyana dzekuparadzanisa.

Tafura 3.Kuchena kwechigadzirwa kunowanikwa kubva kune nzira dzakasiyana dzekuparadzanisa

kuti uwedzere kuvandudza.Kuchena kwechigadzirwa kunosvika pa99%,uye goho ndiro zvakare repamusoro-soro munzira dzakawanda,kusvika pa45%o.1 Nzira yacho inoda 1,1,3-trichloroacetone content yeK inodarika 50% muchloride. solutiono.

Sarudza yakakodzera compound amine catalyst, control slow chlorine blocking in early and late at 10 ~ 30°C, inogona kugadzira 1,1,3-trichloroacetone chloride, yakacheneswa ne special solvent crystallization, iwane crystalline chigadzirwa chisingasviki 99.0%, negoho ye45%, asi 1,1,3-trichloroacetone mumushonga wechloride inofanira kuva yakakura kudarika 50%o.Athena CEO

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