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Pharmaceutical intermediates inoreva mamwe makemikari zvigadzirwa kana makemikari zvigadzirwa zvinoshandiswa mumishonga synthesis process.
Zvinoenderana neindasitiri, indasitiri yemishonga yepakati, sendima yakakosha yeindasitiri yemakemikari yakanaka, ichave nenzvimbo yakakura yekusimudzira mune ramangwana.
| Product | CAS |
| N,N-Dimethyl-p-toluidine DMPT | 99-97-8 |
| N,N-Dimethyl-o-toluidine DMOT | 609-72-3 |
| 2,3-Dichlorobenzaldehyde | 6334-18-5 |
| 2′,4′-Dichloroacetophenone | 2234-16-4 |
| 2,4-Dichlorobenzyl doro | 1777-82-8 |
| 3,4′-Dichlorodiphenyl ether | 6842-62-2 |
| 2-chloro-4-(4-chlorophenoxy)acetophenone | 119851-28-4 |
| 2, 4-dichloroluene | 95-73-8 |
| o-Phenylenediamine | 95-54-5 |
| o-Toluidine OT | 95-53-4 |
| 3-Methyl-N,N-diethyl aniline | 91-67-8 |
| N,N-Diethyl aniline | 91-66-7 |
| N-Ethylaniline | 103-69-5 |
| N-Ethyl-o-toluidine | 94-68-8 |
| N,N-Dimethylaniline DMA | 121-69-7 |
| 2-Nafitori Beta naphthol | 135-19-3 |
| Auramine O | 2465-27-2 |
| Crystal violet lactone CVL | 1552-42-7 |
Kubva munhoroondo yebudiriro yeindasitiri yezvemishonga yeChina, mushure memakore anoda kusvika makumi matatu ebudiriro, vepakati vemishonga vakagadzira kubva kubazi diki reindasitiri yemakemikari kuita indasitiri iri kusimukira ine kukosha kwemabhiriyoni emayuan, uye makwikwi emusika ari kuramba achiwedzera. .
Zvinonzwisiswa kuti muchikamu chekutanga chekuvandudzwa kweindasitiri yemishonga yepakati, nekuda kwekudyara kudiki uye huwandu hwekudzoka, mabhizinesi epakati pemishonga anomera senge bamboo nhungirwa mushure mekunaya kwemvura, kunyanya muZhejiang, Taizhou, Nanjing nedzimwe nzvimbo dzakanaka. mamiriro ekugadzirwa kwemishonga intermediates kukura kunonyanya kukurumidza.
Parizvino, sekuchinja kwemaitiro emusika wekurapa, pamwe nekugadzirwa kwemishonga mitsva pamusika kushoma, kuomerwa kwemishonga inopindirana neindasitiri yekugadzirwa kwechigadzirwa kunowedzera kukura, chigadzirwa chechinyakare chiri kuramba chichiwedzera kukwikwidza kunotyisa. , Pharmaceutical intermediates indasitiri purofiti yakadonha nekukurumidza, uye vepakati vemishonga vanova vanofanirwa kufunga nezve dambudziko rekusimudzira kwebhizinesi.
Iyo indasitiri inotenda kuti zvingaite kuumba yayo yemakwikwi mabhenefiti kubva kuzvinhu zvetekinoroji, pesvedzero, shanduko uye zvichingodaro, kuitira kumira kunze mumusika.
Panyaya yetekinoroji, inonyanya kureva kuvandudza tekinoroji uye mari yekuchengetedza.
Zvinoshumwa kuti vepakati vemishonga vane nzira refu, maitiro akawanda ekuita, huwandu hukuru hwekunyungudutsa, uye mukana mukuru wekuvandudza tekinoroji.
Semuyenzaniso, yakaderera kukosha mbishi zvinhu zvinogona kushandiswa pachinzvimbo chepamusoro kukosha kwezvinhu mbishi, senge inotsiva bromine mukugadzirwa kweaminotaxime acid, ammonium thiocyanate pachinzvimbo che potassium thiocyanate (sodium) mukugadzira, nezvimwe.
Uye zvakare, imwe solvent inogona zvakare kushandiswa kutsiva zvakasiyana zvinonyungudutsa mukuita maitiro, uye doro rinogadzirwa ne hydrolysis yezvigadzirwa zve ester zvinogona kudzoserwa.
Muchikamu chekupesvedzera, inonyanya kuumba zvigadzirwa zvayo zvehunhu uye kugadzirisa pesvedzero muindasitiri.
Zvinonzwisiswa kuti nekuda kweChina chemishonga yepakati indasitiri, chigadzirwa homogenization kukwikwidza kwakakomba, kana bhizinesi richigona kugadzira zvigadzirwa zvaro zvepamusoro, rinozokwanisa kutora mamwe mabhenefiti mumusika.
Panyaya yeshanduko, pari zvino, nezvinodiwa zvekuchengetedzwa kwezvakatipoteredza zvichiwedzera kusimba, zviwanikwa zvakarerekera kumaindasitiri akawedzera kukosha, uye nekuwedzera kwemitengo yekuchengetedza kwezvakatipoteredza, shanduko yave dambudziko iro mabhizinesi epakati pemishonga anofanirwa kufunga nezvayo. budiriro inogoneka.
Zvinokurudzirwa kuti mabhizinesi epakati pemishonga awedzere cheni yeindasitiri kumusoro nekudzika, uye kuendesa iwo makuru zvigadzirwa zvavanoshandisa kune yavo kugadzira, izvo zvinogona kuwedzera kudzikisa mutengo. Zvichakadaro, kune zvimwe zvakakosha zvigadzirwa, zvinogona kudzivirira iyo monopoly yezvinhu zvakakosha mbishi.
Indasitiri inotaura kuti kufamba mumugwagwa, uko mishonga yepakati inobatanidzwa zvakananga mumaAPIs, inogona kuwedzera kuwedzera kukosha kwezvigadzirwa pavanenge vachizvitengesa zvakananga kumakambani emishonga.
Zvakakosha kucherechedza kuti mari yekudyara yakadzika yakakura, nepo zvinodiwa zvetekinoroji zvakakwirira, uye zvinodikanwa kuchengetedza hukama hwakanaka nevagadziri vanoshandisa API.
Pakazara, mabhizinesi anotungamira anogona kuwana mamwe mabhenefiti emakwikwi.
Pamusoro pezvo, kutsvagisa nekusimudzira kwakakosha zvikuru kuindasitiri yepakati. Parizvino, indasitiri yepakati yemishonga muChina kazhinji haitarise zvishoma kutsvagisa nekusimudzira.
Naizvozvo, munharaunda yekugara ichivandudza tekinoroji zvinodiwa, anoshanda maR & D mabhizinesi ane yakasimba R & D simba achauya kumberi, nepo madiki uye epakati mabhizinesi asina R & D kugona anogona kubviswa nemusika. Mune ramangwana, iyo indasitiri yekumisikidzwa ichawedzera kuwedzera, uye yepakati uye yakaderera yekupedzisira nhanho yekusimudzira inosimudzira kusvika padanho repamusoro.
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Nguva yekutumira: Kubvumbi-25-2021